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TitleSelective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 101, Page 3242-3247, Year 2004
Publish dateJun 4, 2003 (structure data deposition date)
AuthorsShen, Y. / Zhukovskaya, N.L. / Zimmer, M.I. / Soelaiman, S. / Bergson, P. / Wang, C.R. / Gibbs, C.S. / Tang, W.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:14978283
MethodsX-ray diffraction
Resolution3.3 Å
Structure data

PDB-1pk0:
Crystal Structure of the EF3-CaM complexed with PMEApp
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-YB:
YTTERBIUM (III) ION

ChemComp-EMA:
(ADENIN-9-YL-ETHOXYMETHYL)-HYDROXYPHOSPHINYL-DIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • bacillus anthracis (anthrax bacterium)
  • homo sapiens (human)
Keywordslyase/metal binding protein / edema factor / CaM / prodrug complex / lyase-metal binding protein COMPLEX

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