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Structure paper

TitleA PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 16463-16470, Year 2004
Publish dateDec 3, 2003 (structure data deposition date)
AuthorsPernot, L. / Chesnel, L. / Le Gouellec, A. / Croize, J. / Vernet, T. / Dideberg, O. / Dessen, A.
External linksJ. Biol. Chem. / PubMed:14734544
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-1rp5:
PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • streptococcus pneumoniae (bacteria)
KeywordsTRANSPEPTIDASE / PENICILLIN-BINDING PROTEIN / ANTIBIOTIC RESISTANCE / PEPTIDOGLYCAN SYNTHESIS / CELL WALL / TRANSMEMBRANE

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