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TitleCrystal Structure of Human Thymidine Phosphorylase in Complex with a Small Molecule Inhibitor
Journal, issue, pagesStructure, Vol. 12, Page 75-, Year 2004
Publish dateSep 23, 2003 (structure data deposition date)
AuthorsNorman, R.A. / Barry, S.T. / Bate, M. / Breed, J. / Colls, J.G. / Ernill, R.J. / Luke, R.W.A. / Minshull, C.A. / Mcalister, M.S.B. / Mccall, E.J. ...Norman, R.A. / Barry, S.T. / Bate, M. / Breed, J. / Colls, J.G. / Ernill, R.J. / Luke, R.W.A. / Minshull, C.A. / Mcalister, M.S.B. / Mccall, E.J. / Mcmicken, H.H.J. / Paterson, D.S. / Timms, D. / Tucker, J.A. / Pauptit, R.A.
External linksStructure / PubMed:14725767
MethodsX-ray diffraction
Resolution2.11 Å
Structure data

PDB-1uou:
Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

Chemicals

ChemComp-CMU:
5-CHLORO-6-(1-(2-IMINOPYRROLIDINYL) METHYL) URACIL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PHOSPHORYLASE / GLYCOSYLTRANSFERASE / CHEMOTAXIS / ANGIOGENESIS

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