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TitleExploration of the P1 SAR of aldehyde cathepsin K inhibitors
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 14, Page 275-278, Year 2004
Publish dateAug 13, 2003 (structure data deposition date)
AuthorsCatalano, J.G. / Deaton, D.N. / Furfine, E.S. / Hassell, A.M. / McFadyen, R.B. / Miller, A.B. / Miller, L.R. / Shewchuk, L.M. / Willard, D.H. / Wright, L.L.
External linksBioorg. Med. Chem. Lett. / PubMed:14684342
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1q6k:
Cathepsin K complexed with t-butyl(1S)-1-cyclohexyl-2-oxoethylcarbamate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-TCO:
TERT-BUTYL(1S)-1-CYCLOHEXYL-2-OXOETHYLCARBAMATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / cathepsin K / catK

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