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Structure paper

TitleExpression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes.
Journal, issue, pagesJ. Biol. Chem., Vol. 279, Page 7223-7228, Year 2004
Publish dateNov 18, 2003 (structure data deposition date)
AuthorsWhittington, D.A. / Grubb, J.H. / Waheed, A. / Shah, G.N. / Sly, W.S. / Christianson, D.W.
External linksJ. Biol. Chem. / PubMed:14660577
MethodsX-ray diffraction
Resolution2.81 - 2.9 Å
Structure data

PDB-1rj5:
Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV
Method: X-RAY DIFFRACTION / Resolution: 2.81 Å

PDB-1rj6:
Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV in Complex with Acetazolamide
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

ChemComp-AZM:
5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE / medication*YM

Source
  • mus musculus (house mouse)
KeywordsLYASE / beta-sheet / alpha-helix / zinc enzyme

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