+Search query
-Structure paper
Title | Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 urea leads to potent intracellular inhibitors of hepatitis C virus NS3/4A protease |
---|---|
Journal, issue, pages | Org. Lett., Vol. 5, Page 4627-4630, Year 2003 |
Publish date | Dec 10, 2003 (structure data deposition date) |
![]() | Slater, M.J. / Amphlett, E.M. / Andrews, D.M. / Bamborough, P. / Carey, S.J. / Johnson, M.R. / Jones, P.S. / Mills, G. / Parry, N.R. / Somers, D.O. ...Slater, M.J. / Amphlett, E.M. / Andrews, D.M. / Bamborough, P. / Carey, S.J. / Johnson, M.R. / Jones, P.S. / Mills, G. / Parry, N.R. / Somers, D.O. / Stewart, A.J. / Skarzynski, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.75 Å |
Structure data | ![]() PDB-1rtl: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CPX: ![]() ChemComp-HOH: |
Source |
|
![]() | Viral protein complex / VIRAL PROTEIN / SERINE PROTEASE / NONSTRUCTURAL PROTEIN / COFACTOR PEPTIDE / HELICASE / INHIBITOR / TRANSLACTAM |