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TitleCrystal Structure of an Acyl-ACP Dehydrogenase from the FK520 Polyketide Biosynthetic Pathway: Insights into Extender Unit Biosynthesis
Journal, issue, pagesJ. Mol. Biol., Vol. 334, Page 435-444, Year 2003
Publish dateSep 28, 2003 (structure data deposition date)
AuthorsWatanabe, K. / Khosla, C. / Stroud, R.M. / Tsai, S.-C.
External linksJ. Mol. Biol. / PubMed:14623185
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1r2j:
FkbI for Biosynthesis of Methoxymalonyl Extender Unit of Fk520 Polyketide Immunosuppresant
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-HOH:
WATER

Source
  • streptomyces hygroscopicus (bacteria)
KeywordsOXIDOREDUCTASE / FK520; FK506; polyketide synthase; polyketide; acyl-CoA dehydrogenase; crystal structure; aldehyde dehydrogenase

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