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Structure paper

TitleStructural Basis of Aurora-A Activation by Tpx2 at the Mitotic Spindle
Journal, issue, pagesMol. Cell, Vol. 12, Page 851-, Year 2003
Publish dateAug 6, 2003 (structure data deposition date)
AuthorsBayliss, R. / Sardon, T. / Vernos, I. / Conti, E.
External linksMol. Cell / PubMed:14580337
MethodsX-ray diffraction
Resolution2.5 - 3 Å
Structure data

PDB-1ol5:
Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1ol6:
Structure of unphosphorylated D274N mutant of Aurora-A
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1ol7:
Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/CELL CYCLE / TRANSFERASE-CELL CYCLE COMPLEX / CELL CYCLE / TRANSFERASE / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING / PHOSPHORYLATION / KINASE

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