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TitleCrystallographic Studies on the Complex Behavior of Nicotine Binding to P450cam (CYP101)(dagger).
Journal, issue, pagesBiochemistry, Vol. 42, Page 11943-11950, Year 2003
Publish dateApr 16, 2003 (structure data deposition date)
AuthorsStrickler, M. / Goldstein, B.M. / Maxfield, K. / Shireman, L. / Kim, G. / Matteson, D. / Jones, J.P.
External linksBiochemistry / PubMed:14556625
MethodsX-ray diffraction
Resolution2.3 - 2.85 Å
Structure data

PDB-1p2y:
CRYSTAL STRUCTURE OF CYTOCHROME P450CAM IN COMPLEX WITH (S)-(-)-NICOTINE
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1p7r:
CRYSTAL STRUCTURE OF REDUCED, CO-EXPOSED COMPLEX OF CYTOCHROME P450CAM WITH (S)-(-)-NICOTINE
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-NCT:
(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • pseudomonas putida (bacteria)
KeywordsOXIDOREDUCTASE / MONOOXYGENASE / HEME / NICOTINE

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