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TitleCrystal structure of IRF-3 reveals mechanism of autoinhibition and virus induced phospho-activation
Journal, issue, pagesNat. Struct. Biol., Vol. 10, Page 913-921, Year 2003
Publish dateSep 3, 2003 (structure data deposition date)
AuthorsQin, B.Y. / Liu, C. / Lam, S.S. / Srinath, H. / Delston, R. / Correia, J.J. / Derynck, R. / Lin, K.
External linksNat. Struct. Biol. / PubMed:14555996
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1qwt:
Auto-inhibitory interferon regulation factor-3 (IRF3) transactivation domain
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN

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