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TitleSU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 310, Page 1026-1031, Year 2003
Publish dateMay 24, 2003 (structure data deposition date)
AuthorsMoshinsky, D.J. / Bellamacina, C.R. / Boisvert, D.C. / Huang, P. / Hui, T. / Jancarik, J. / Kim, S.H. / Rice, A.G.
External linksBiochem. Biophys. Res. Commun. / PubMed:14550307
MethodsX-ray diffraction
Resolution2.51 Å
Structure data

PDB-1pf8:
Crystal Structure of Human Cyclin-Dependent Kinase 2 Complexed with a Nucleoside Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-SU9:
(3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SERINE/THREONINE PROTEIN KINASE / ATP-BINDING / CELL CYCLE / CELL DIVISION / MITOSIS / PHOSPHORYLATION / SU9516 / INHIBITOR

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