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Structure paper

TitleProteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors.
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 52964-52971, Year 2003
Publish dateSep 18, 2003 (structure data deposition date)
AuthorsTowbin, H. / Bair, K.W. / DeCaprio, J.A. / Eck, M.J. / Kim, S. / Kinder, F.R. / Morollo, A. / Mueller, D.R. / Schindler, P. / Song, H.K. ...Towbin, H. / Bair, K.W. / DeCaprio, J.A. / Eck, M.J. / Kim, S. / Kinder, F.R. / Morollo, A. / Mueller, D.R. / Schindler, P. / Song, H.K. / van Oostrum, J. / Versace, R.W. / Voshol, H. / Wood, J. / Zabludoff, S. / Phillips, P.E.
External linksJ. Biol. Chem. / PubMed:14534293
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-1qzy:
Human Methionine Aminopeptidase in complex with bengamide inhibitor LAF153 and cobalt
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-CO:
Unknown entry

ChemComp-TDE:
(E)-(2R,3R,4S,5R)-3,4,5-TRIHYDROXY-2-METHOXY-8,8-DIMETHYL-NON-6-ENOIC ACID ((3S,6R)-6-HYDROXY-2-OXO-AZEPAN-3-YL)-AMIDE

ChemComp-TBU:
TERTIARY-BUTYL ALCOHOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE

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