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TitleDesign of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features
Journal, issue, pagesBiochemistry, Vol. 42, Page 11701-11706, Year 2003
Publish dateAug 9, 2002 (structure data deposition date)
AuthorsSingh, R.K. / Vikram, P. / Makker, J. / Jabeen, T. / Sharma, S. / Dey, S. / Kaur, P. / Srinivasan, A. / Singh, T.P.
External linksBiochemistry / PubMed:14529280
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1mf4:
Structure-based design of potent and selective inhibitors of phospholipase A2: Crystal structure of the complex formed between phosholipase A2 from Naja Naja sagittifera and a designed peptide inhibitor at 1.9 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • naja sagittifera (cobra)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Naja naja sagittifera / phospholipase A2 / designed inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex

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