EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B
ジャーナル・号・ページ	Biochemistry, Vol. 42, Page 11451-11459, Year 2003
掲載日	2003年8月13日 (構造データの登録日)
著者	Scapin, G. / Patel, S.B. / Becker, J.W. / Wang, Q. / Desponts, C. / Waddleton, D. / Skorey, K. / Cromlish, W. / Bayly, C. / Therien, M. ...Scapin, G. / Patel, S.B. / Becker, J.W. / Wang, Q. / Desponts, C. / Waddleton, D. / Skorey, K. / Cromlish, W. / Bayly, C. / Therien, M. / Gauthier, J.Y. / Li, C.S. / Lau, C.K. / Ramachandran, C. / Kennedy, B.P. / Asante-Appiah, E.
リンク	Biochemistry / PubMed:14516196
手法	X線回折
解像度	2.1 - 2.3 Å
構造データ	PDB-1q6j: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 2 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-1q6m: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 3 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-1q6n: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 4 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-1q6p: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 6 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-1q6s: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 9 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-1q6t: THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 11 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å
化合物	ChemComp-335: [4-(2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL](DIFLUORO)METHYLPHOSPHONIC ACID ChemComp-HOH: WATER ChemComp-P27: {[2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-2-(3,4-DIFLUOROPHENYL)PROPANE-1,3-DIYL]BIS[4,1-PHENYLENE(DIFLUOROMETHYLENE)]}BIS(PHOSPHONIC ACID) ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-CL: Unknown entry / クロリド ChemComp-P90: {4-[(2S,4E)-2-(1,3-BENZOTHIAZOL-2-YL)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-5-PHENYLPENT-4-ENYL]PHENYL}(DIFLUORO)METHYLPHOSPHONIC ACID ChemComp-213: 4'-((2S)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)-1,1'-BIPHENYL-3-YLPHOSPHONIC ACID ChemComp-214: 6-[4-((2R)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL]-2-METHYLQUINOLIN-8-YLPHOSPHONIC ACID ChemComp-MPD: (4S)-2-METHYL-2,4-PENTANEDIOL / (S)-2-メチル-2,4-ペンタンジオ-ル / 沈殿剤YM ChemComp-600*: 6-[4-((2S)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL]-2-[(1S)-1-METHOXY-3-METHYLBUTYL]QUINOLIN-8-YLPHOSPHONIC ACID
由来	homo sapiens (ヒト)
キーワード	HYDROLASE / PHOSPHATASE / SECONDARY BINDING SITE / SELECTIVITY