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TitleHelix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 100, Page 11273-11278, Year 2003
Publish dateMay 16, 2003 (structure data deposition date)
AuthorsLeduc, A.M. / Trent, J.O. / Wittliff, J.L. / Bramlett, K.S. / Briggs, S.L. / Chirgadze, N.Y. / Wang, Y. / Burris, T.P. / Spatola, A.F.
External linksProc. Natl. Acad. Sci. USA / PubMed:13679575
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-1pcg:
Helix-stabilized cyclic peptides as selective inhibitors of steroid receptor-coactivator interactions
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-EST:
ESTRADIOL / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/INHIBITOR / co-activator binding site / TRANSCRIPTION-INHIBITOR COMPLEX

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