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TitleStructural basis for inhibition of human PNP by immucillin-H
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 309, Page 917-922, Year 2003
Publish dateMay 24, 2003 (structure data deposition date)
AuthorsDe Azevedo Jr., W.F. / Canduri, F. / Dos Santos, D.M. / Pereira, J.H. / Dias, M.V.B. / Silva, R.G. / Mendes, M.A. / Palma, M.S. / Basso, L.A. / Santos, D.S.
External linksBiochem. Biophys. Res. Commun. / PubMed:13679061
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1pf7:
CRYSTAL STRUCTURE OF HUMAN PNP COMPLEXED WITH IMMUCILLIN H
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-IMH:
1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PURINE NUCLEOSIDE PHOSPHORYLASE / DRUG DESIGN / SYNCHROTRON

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