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TitleExploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 44904-44912, Year 2003
Publish dateJul 9, 2003 (structure data deposition date)
AuthorsZavala-Ruiz, Z. / Sundberg, E.J. / Stone, J.D. / DeOliveira, D.B. / Chan, I.C. / Svendsen, J. / Mariuzza, R.A. / Stern, L.J.
External linksJ. Biol. Chem. / PubMed:12952957
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-1pyw:
Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • staphylococcus aureus subsp. aureus mu50 (bacteria)
KeywordsIMMUNE SYSTEM/PROTEIN BINDING/TOXIN / MHC class II / Major histocompatibility protein complex / HLA-DR1 / Influenza / Hemagglutinin / Superantigen / Antigen / IMMUNE SYSTEM-PROTEIN BINDING-TOXIN COMPLEX

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