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-Structure paper
Title | Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone. |
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Journal, issue, pages | J. Med. Chem., Vol. 46, Page 3865-3876, Year 2003 |
Publish date | Dec 4, 2002 (structure data deposition date) |
![]() | Costanzo, M.J. / Yabut, S.C. / Almond Jr., H.R. / Andrade-Gordon, P. / Corcoran, T.W. / De Garavilla, L. / Kauffman, J.A. / Abraham, W.M. / Recacha, R. / Chattopadhyay, D. / Maryanoff, B.E. |
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Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-1nc6: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-SO4: ![]() ChemComp-ABB: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / protein-inhibitor complex |