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Structure paper

TitleControl of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase.
Journal, issue, pagesNat. Struct. Biol., Vol. 10, Page 757-763, Year 2003
Publish dateJun 26, 2003 (structure data deposition date)
AuthorsBreinig, S. / Kervinen, J. / Stith, L. / Wasson, A.S. / Fairman, R. / Wlodawer, A. / Zdanov, A. / Jaffe, E.K.
External linksNat. Struct. Biol. / PubMed:12897770
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1pv8:
Crystal structure of a low activity F12L mutant of human porphobilinogen synthase
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-PB1:
3-(2-AMINOETHYL)-4-(AMINOMETHYL)HEPTANEDIOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / PORPHOBILINOGEN SYNTHASE / TETRAPYRROLE BIOSYNTHESIS / REACTION INTERMEDIATE

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