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TitleThree-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Journal, issue, pagesStructure, Vol. 11, Page 865-873, Year 2003
Publish dateApr 5, 2003 (structure data deposition date)
AuthorsHuai, Q. / Wang, H. / Sun, Y. / Kim, H.Y. / Liu, Y. / Ke, H.
External linksStructure / PubMed:12842049
MethodsX-ray diffraction
Resolution2 - 2.3 Å
Structure data

PDB-1oyn:
Crystal structure of PDE4D2 in complex with (R,S)-rolipram
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1q9m:
Three dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ROL:
ROLIPRAM / antidepressant, inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PDE / cAMP / rolipram / specific inhibitor

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