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Structure paper

TitleStructural insight into the antibiotic action of telithromycin against resistant mutants
Journal, issue, pagesJ. Bacteriol., Vol. 185, Page 4276-4279, Year 2003
Publish dateMay 13, 2003 (structure data deposition date)
AuthorsBerisio, R. / Harms, J. / Schluenzen, F. / Zarivach, R. / Hansen, H.A. / Fucini, P. / Yonath, A.
External linksJ. Bacteriol. / PubMed:12837804
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-1p9x:
THE CRYSTAL STRUCTURE OF THE 50S LARGE RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS COMPLEXED WITH TELITHROMYCIN KETOLIDE ANTIBIOTIC
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-TEL:
TELITHROMYCIN / antibiotic*YM

Source
  • deinococcus radiodurans (radioresistant)
KeywordsRIBOSOME / RIBOSOMES / TRNA / KETOLIDE / MACROLIDE / ANTIBIOTIC / EXIT-TUNNEL / BLOCKAGE

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