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TitleBiochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).
Journal, issue, pagesBiochem. J., Vol. 374, Page 639-646, Year 2003
Publish dateFeb 24, 2003 (structure data deposition date)
AuthorsSarno, S. / de Moliner, E. / Ruzzene, M. / Pagano, M.A. / Battistutta, R. / Bain, J. / Fabbro, D. / Schoepfer, J. / Elliott, M. / Furet, P. ...Sarno, S. / de Moliner, E. / Ruzzene, M. / Pagano, M.A. / Battistutta, R. / Bain, J. / Fabbro, D. / Schoepfer, J. / Elliott, M. / Furet, P. / Meggio, F. / Zanotti, G. / Pinna, L.A.
External linksBiochem. J. / PubMed:12816539
MethodsX-ray diffraction
Resolution1.68 Å
Structure data

PDB-1om1:
Crystal structure of maize CK2 alpha in complex with IQA
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

Chemicals

ChemComp-IQA:
(5-OXO-5,6-DIHYDRO-INDOLO[1,2-A]QUINAZOLIN-7-YL)-ACETIC ACID

ChemComp-HOH:
WATER

Source
  • zea mays (maize)
KeywordsTRANSFERASE / CK2 / IQA / inhibitor / Zea mays

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