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TitleX-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease
Journal, issue, pagesEmbo Rep., Vol. 4, Page 704-, Year 2003
Publish dateMay 13, 2003 (structure data deposition date)
AuthorsDvir, H. / Harel, M. / Mccarthy, A.A. / Toker, L. / Silman, I. / Futerman, A.H. / Sussman, J.L.
External linksEmbo Rep. / PubMed:12792654
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1ogs:
human acid-beta-glucosidase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / GAUCHER DISEASE / GLUCOSIDASE / GLUCOCEREBROSIDASE / CEREZYME HYDROLASE / GLYCOSIDASE / SPHINGOLIPID METABOLISM / GLYCOPROTE LYSOSOME / MEMBRANE / DISEASE MUTATI POLYMORPHISM / ALTERNATIVE INITIATION / PHARMACEUTICAL / ISRAEL STRUCTURAL PROTEOMICS CENTER / ISPC / STRUCTURAL GENOMICS

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