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Structure paper

TitleStructural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway:Studies of the Drosophila Deoxyribonucleoside Kinase
Journal, issue, pagesBiochemistry, Vol. 42, Page 5706-, Year 2003
Publish dateMar 17, 2003 (structure data deposition date)
AuthorsMikkelsen, N.E. / Johansson, K. / Karlsson, A. / Knecht, W. / Andersen, G. / Piskur, J. / Munch-Petersen, B. / Eklund, H.
External linksBiochemistry / PubMed:12741827
MethodsX-ray diffraction
Resolution2.4 - 2.5 Å
Structure data

PDB-1oe0:
CRYSTAL STRUCTURE OF DROSOPHILA DEOXYRIBONUCLEOSIDE KINASE IN COMPLEX WITH DTTP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1ot3:
Crystal structure of Drosophila deoxyribonucleotide kinase complexed with the substrate deoxythymidine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-TTP:
THYMIDINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-THM:
THYMIDINE

Source
  • drosophila melanogaster (fruit fly)
KeywordsTRANSFERASE / DROSOPHILA / DEOXYRIBONUCLEOSIDE KINASE / DTTP / COMPLEX / FEEDBACK INHIBITION / SALVAGE PATHWAY / protein-deoxynucleoside complex

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