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| Title | Crystal Structure of Human Carboxylesterase 1 Complexed with the Alzheimer's Drug Tacrine: From Binding Promiscuity to Selective Inhibition |
|---|---|
| Journal, issue, pages | CHEM. BIOL., Vol. 10, Page 341-349, Year 2003 |
| Publish date | Oct 1, 2002 (structure data deposition date) |
Authors | Bencharit, S. / Morton, C.L. / Hyatt, J.L. / Kuhn, P. / Danks, M.K. / Potter, P.M. / Redinbo, M.R. |
External links | CHEM. BIOL. / PubMed:12725862 |
| Methods | X-ray diffraction |
| Resolution | 2.4 Å |
| Structure data | ![]() PDB-1mx1: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-SIA: ![]() ChemComp-THA: ![]() ChemComp-HOH: |
| Source |
|
Keywords | HYDROLASE / esterase / esterase inhibitor |
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homo sapiens (human)
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