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TitleStructural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 26007-26014, Year 2003
Publish dateApr 11, 2003 (structure data deposition date)
AuthorsLi, S. / Covino, N.D. / Stein, E.G. / Till, J.H. / Hubbard, S.R.
External linksJ. Biol. Chem. / PubMed:12707268
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1p14:
Crystal structure of a catalytic-loop mutant of the insulin receptor tyrosine kinase
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / RECEPTOR / TYROSINE KINASE / CATALYSIS / MUTANT

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