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| Title | The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain: RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM. |
|---|---|
| Journal, issue, pages | J. Biol. Chem., Vol. 278, Page 22748-22754, Year 2003 |
| Publish date | Dec 20, 2002 (structure data deposition date) |
Authors | Kauppi, B. / Jakob, C. / Farnegardh, M. / Yang, J. / Ahola, H. / Alarcon, M. / Calles, K. / Engstrom, O. / Harlan, J. / Muchmore, S. ...Kauppi, B. / Jakob, C. / Farnegardh, M. / Yang, J. / Ahola, H. / Alarcon, M. / Calles, K. / Engstrom, O. / Harlan, J. / Muchmore, S. / Ramqvist, A.-K. / Thorell, S. / Ohman, L. / Greer, J. / Gustafsson, J.-A. / Carlstedt-Duke, J. / Carlquist, M. |
External links | J. Biol. Chem. / PubMed:12686538 |
| Methods | X-ray diffraction |
| Resolution | 2.3 - 2.7 Å |
| Structure data | ![]() PDB-1nhz: ![]() PDB-1p93: |
| Chemicals | ![]() ChemComp-486: ![]() ChemComp-HEZ: ![]() ChemComp-HOH: ![]() ChemComp-DEX: |
| Source |
|
Keywords | Hormone receptor / PROTEIN-LIGAND COMPLEX / ANTI PARALLEL ALPHA HELIX SANDWICH |
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homo sapiens (human)
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