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Structure paper

TitleCrystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
Journal, issue, pagesBIOCHEM. BIOPHYS. ACTA PROTEINS & PROTEOMICS, Vol. 1647, Page 325-332, Year 2003
Publish dateJun 1, 2002 (structure data deposition date)
AuthorsOikonomakos, N.G. / Chrysina, E.D. / Kosmopoulou, M.N. / Leonidas, D.D.
External linksBIOCHEM. BIOPHYS. ACTA PROTEINS & PROTEOMICS / PubMed:12686153
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1lwn:
Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1lwo:
Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GLC:
alpha-D-glucopyranose

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-CHI:
5-CHLORO-1H-INDOLE-2-CARBOXYLIC ACID [1-(4-FLUOROBENZYL)-2-(4-HYDROXYPIPERIDIN-1YL)-2-OXOETHYL]AMIDE

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE / type 2 diabetes / glycogen phosphorylase / inhibitor / new allosteric site

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