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TitleLeads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
Journal, issue, pagesJ. Biol. Chem., Vol. 278, Page 21774-, Year 2003
Publish dateMar 10, 2003 (structure data deposition date)
AuthorsFernandez-Tornero, C. / Lozano, R.M. / Redondo-Horcajo, M. / Gomez, A. / Lopez, J. / Quesada, E. / Uriel, C. / Valverde, S. / Cuevas, P. / Romero, A. / Gimenez-Gallego, G.
External linksJ. Biol. Chem. / PubMed:12676958
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1hkn:
A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-N2M:
5-AMINO-NAPHTALENE-2-MONOSULFONATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsGROWTH FACTOR / MITOGEN / ANGIOGENESIS / HEPARIN-BINDING

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