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TitleCrystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Journal, issue, pagesChem. Biol., Vol. 10, Page 139-147, Year 2003
Publish dateJan 16, 2003 (structure data deposition date)
AuthorsDavies, D.R. / Interthal, H. / Champoux, J.J. / Hol, W.G.J.
External linksChem. Biol. / PubMed:12618186
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1nop:
Crystal structure of human tyrosyl-DNA phosphodiesterase (Tdp1) in complex with vanadate, DNA and a human topoisomerase I-derived peptide
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-VO4:
VANADATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA / PROTEIN-DNA COMPLEX / vanadate complex / transition state mimic / HYDROLASE-DNA COMPLEX

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