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Structure paper

TitleStructure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 59, Page 23-31, Year 2003
Publish dateMar 11, 2002 (structure data deposition date)
AuthorsKishida, H. / Wada, T. / Unzai, S. / Kuzuyama, T. / Takagi, M. / Terada, T. / Shirouzu, M. / Yokoyama, S. / Tame, J.R. / Park, S.Y.
External linksActa Crystallogr. ,Sect. D / PubMed:12499535
MethodsX-ray diffraction
Resolution1.52 - 1.65 Å
Structure data

PDB-1iv1:
Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-1iv2:
Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase (bound form CDP)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-1iv3:
Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase (bound form MG atoms)
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

PDB-1iv4:
Structure of 2C-Methyl-D-erythritol-2,4-cyclodiphosphate Synthase (bound form Substrate)
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-CDP:
CYTIDINE-5'-DIPHOSPHATE

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

Source
  • thermus thermophilus (bacteria)
KeywordsLYASE / isoprenoid / non-mevalonate / synthase / RIKEN Structural Genomics/Proteomics Initiative / RSGI / Structural Genomics

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