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TitleDiabetes mutations delineate an atypical POU domains in HNF1-Alpha
Journal, issue, pagesMol. Cell, Vol. 10, Page 1129-1137, Year 2002
Publish dateMar 30, 2001 (structure data deposition date)
AuthorsChi, Y.-I. / Frantz, J.D. / Oh, B.-C. / Hansen, L. / Dhe-Paganon, S. / Shoelson, S.E.
External linksMol. Cell / PubMed:12453420
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1ic8:
HEPATOCYTE NUCLEAR FACTOR 1A BOUND TO DNA : MODY3 GENE PRODUCT
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / Transcription regulation; DNA-binding; POU domain; diabetes; Disease mutation; MODY3 / TRANSCRIPTION-DNA COMPLEX

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