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TitleInsights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase.
Journal, issue, pagesJ. Mol. Biol., Vol. 324, Page 247-256, Year 2002
Publish dateOct 16, 2002 (structure data deposition date)
AuthorsCardoso, R.M.F. / Thayer, M.M. / DiDonato, M. / Lo, T.P. / Bruns, C.K. / Getzoff, E.D. / Tainer, J.A.
External linksJ. Mol. Biol. / PubMed:12441104
MethodsX-ray diffraction
Resolution1.86 - 2 Å
Structure data

PDB-1n18:
Thermostable mutant of Human Superoxide Dismutase, C6A, C111S
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-1n19:
Structure of the HSOD A4V mutant
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

Chemicals

ChemComp-CU1:
COPPER (I) ION

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / greek key beta barrel / Greek Key beta-barrel

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