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Structure paper

TitleCocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor
Journal, issue, pagesStructure, Vol. 10, Page 1499-1508, Year 2002
Publish dateJun 24, 2004 (structure data deposition date)
AuthorsRajashankar, K. / Ray, S.R. / Bonanno, J.B. / Pinho, M.G. / He, G. / De Lencastre, H. / Tomasz, A. / Burley, S.K.
External linksStructure / PubMed:12429091
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-1tuf:
Crystal structure of Diaminopimelate Decarboxylase from m. jannaschi
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1twi:
Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-AZ1:
AZELAIC ACID

ChemComp-HOH:
WATER

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-LYS:
LYSINE

Source
  • methanocaldococcus jannaschii (archaea)
KeywordsLYASE / antibiotic resistance / diamnopimilate decarboxylase / lysine biosynthesis / structural genomics / NYSGXRC / T135 / PSI / Protein Structure Initiative / New York SGX Research Center for Structural Genomics / diaminopimelate decarboxylase

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