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TitleDesign of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
Journal, issue, pagesACTA CRYSTALLOGR. ,SECT. D, Vol. 58, Page 1813-1819, Year 2002
Publish dateAug 4, 2001 (structure data deposition date)
AuthorsChandra, V. / Jasti, J. / Kaur, P. / Dey, S. / Srinivasan, A. / Betzel, C.h. / Singh, T.P.
External linksACTA CRYSTALLOGR. ,SECT. D / PubMed:12351825
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1jq8:
Design of specific inhibitors of phospholipase A2: Crystal structure of a complex formed between phospholipase A2 from Daboia russelli pulchella and a designed pentapeptide Leu-Ala-Ile-Tyr-Ser at 2.0 resolution
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ACY:
ACETIC ACID

ChemComp-HOH:
WATER

Source
  • daboia russellii pulchella (snake)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / neurotoxic / designed peptide / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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