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Structure paper

TitleA Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Journal, issue, pagesNat. Immunol., Vol. 3, Page 940-, Year 2002
Publish dateJul 2, 2002 (structure data deposition date)
AuthorsLang, H. / Jacobsen, H. / Ikemizu, S. / Andersson, C. / Harlos, K. / Madsen, L. / Hjorth, P. / Sondergaard, L. / Svejgaard, A. / Wucherpfennig, K. ...Lang, H. / Jacobsen, H. / Ikemizu, S. / Andersson, C. / Harlos, K. / Madsen, L. / Hjorth, P. / Sondergaard, L. / Svejgaard, A. / Wucherpfennig, K. / Stuart, D.I. / Bell, J.I. / Jones, E.Y. / Fugger, L.
External linksNat. Immunol. / PubMed:12244309
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-1h15:
X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human herpesvirus 4 (Epstein-Barr virus)
KeywordsIMMUNE SYSTEM/TRANSFERASE / COMPLEX (MHC-ANTIGEN) / IMMUNE SYSTEM / MHC / HLA / CLASS II / DR2 / DRB5 / EBV / DNA POLYMERASE / DNA-DIRECTED DNA POLYMERASE / IMMUNE SYSTEM-TRANSFERASE complex

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