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Structure paper

TitleCrystal Structure of Tritrichomonas foetus Inosine Monophosphate Dehydrogenase in Complex with the Inhibitor Ribavirin Monophosphate Reveals a Catalysis-dependent Ion-binding Site
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 50654-50659, Year 2002
Publish dateAug 8, 2002 (structure data deposition date)
AuthorsProsise, G.L. / Wu, J. / Luecke, H.
External linksJ. Biol. Chem. / PubMed:12235158
MethodsX-ray diffraction
Resolution1.9 - 2.15 Å
Structure data

PDB-1me7:
Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP and MOA bound
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-1me8:
Inosine Monophosphate Dehydrogenase (IMPDH) From Tritrichomonas Foetus with RVP bound
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-RVP:
RIBAVIRIN MONOPHOSPHATE

ChemComp-MOA:
MYCOPHENOLIC ACID / medication, immunosuppressant*YM

ChemComp-HOH:
WATER

Source
  • tritrichomonas foetus (eukaryote)
KeywordsOXIDOREDUCTASE / alpha beta barrel

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