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Structure paper

TitleCrystal Structures of Leukotriene A4 Hydrolase in Complex with Captopril and Two Competitive Tight-Binding Inhibitors
Journal, issue, pagesFaseb J., Vol. 16, Page 1648-, Year 2002
Publish dateDec 7, 2007 (structure data deposition date)
AuthorsThunnissen, M.M.G.M. / Andersson, B. / Wong, C.-H. / Samuelsson, B. / Haeggstrom, J.Z.
External linksFaseb J. / PubMed:12207002
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-2vj8:
Complex of human leukotriene A4 hydrolase with a hydroxamic acid inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-YB:
YTTERBIUM (III) ION

ChemComp-IMD:
IMIDAZOLE

ChemComp-ACT:
ACETATE ION

ChemComp-HA2:
6-[{(2S)-2-AMINO-3-[4-(BENZYLOXY)PHENYL]PROPYL}(HYDROXY)AMINO]-6-OXOHEXANOIC ACID)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / HYDROXAMIC ACID / LEUKOTRIENE HYDROLASE / ZINC / PROTEASE / METALLOPROTEASE

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