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-Structure paper
Title | Analysis of quinazoline and pyrido[2,3-d]pyrimidine N9-C10 reversed-bridge antifolates in complex with NADP+ and Pneumocystis carinii dihydrofolate reductase. |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 58, Page 1393-1399, Year 2002 |
Publish date | Jun 6, 2002 (structure data deposition date) |
![]() | Cody, V. / Galitsky, N. / Luft, J.R. / Pangborn, W. / Queener, S.F. / Gangjee, A. |
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Methods | X-ray diffraction |
Resolution | 1.9 - 2.1 Å |
Structure data | ![]() PDB-1ly3: ![]() PDB-1ly4: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-COG: ![]() ChemComp-HOH: ![]() ChemComp-COQ: |
Source |
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![]() | OXIDOREDUCTASE / pcDHFR reversed bridge antifolates / pcDHFR / N9-C10 reversed bridge pyridopyrimidine antifolate |