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Structure paper

TitleStructural insights into peptide bond formation.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 99, Page 11670-11675, Year 2002
Publish dateJul 26, 2002 (structure data deposition date)
AuthorsHansen, J.L. / Schmeing, T.M. / Moore, P.B. / Steitz, T.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:12185246
MethodsX-ray diffraction
Resolution2.8 - 3.2 Å
Structure data

PDB-1m90:
Co-crystal structure of CCA-Phe-caproic acid-biotin and sparsomycin bound to the 50S ribosomal subunit
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1q7y:
Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-1q81:
Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
Method: X-RAY DIFFRACTION / Resolution: 2.95 Å

PDB-1q82:
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
Method: X-RAY DIFFRACTION / Resolution: 2.98 Å

PDB-1q86:
Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit.
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-SPS:
SPARSOMYCIN

ChemComp-PHA:
PHENYLALANINAL

ChemComp-ACA:
6-AMINOHEXANOIC ACID / inhibitor*YM

ChemComp-CD:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-PUY:
PUROMYCIN / antibiotic, inhibitor*YM

ChemComp-PPU:
PUROMYCIN-5'-MONOPHOSPHATE

Source
  • haloarcula marismortui (Halophile)
KeywordsRIBOSOME / P-site / sparsomycin / ribosome 50S / puromycin / peptidyl transferase reaction / PROTEIN-PROTEIN COMPLEX / RNA-RNA COMPLEX / PROTEIN-RNA COMPLEX / substrate analog / minihelix / A-site

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