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TitleHigh Resolution Structure of the Pleckstrin Homology Domain of Protein Kinase B/Akt Bound to Phosphatidylinositol (3,4,5)-Trisphosphate
Journal, issue, pagesCurr. Biol., Vol. 12, Page 1256-, Year 2002
Publish dateJul 1, 2002 (structure data deposition date)
AuthorsThomas, C.C. / Deak, M. / Alessi, D.R. / Van Aalten, D.M.F.
External linksCurr. Biol. / PubMed:12176338
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-1h10:
HIGH RESOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN OF PROTEIN KINASE B/AKT BOUND TO INS(1,3,4,5)-TETRAKISPHOPHATE
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-4IP:
INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SIGNALLING PROTEIN / PHOSPHOINOSITIDES / PROTEIN KINASE B / PLECKSTRIN / INOSITOL TETRAKISPHOPHATE / PHOSPHORYLATION / SERINE/THREONINE PROTEIN KINASE

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