+Search query
-Structure paper
Title | Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571) |
---|---|
Journal, issue, pages | Cancer Res., Vol. 62, Page 4236-4243, Year 2002 |
Publish date | Apr 10, 2001 (structure data deposition date) |
![]() | Nagar, B. / Bornmann, W. / Pellicena, P. / Schindler, T. / Veach, D.R. / Miller, W.T. / Clarkson, B. / Kuriyan, J. |
![]() | ![]() |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.6 Å |
Structure data | ![]() PDB-1iep: ![]() PDB-1m52: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-STI: ![]() ChemComp-HOH: ![]() ChemComp-P17: ![]() ChemComp-MES: |
Source |
|
![]() | TRANSFERASE / KINASE / KINASE INHIBITOR / STI-571 / ACTIVATION LOOP / PD173955 |