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Structure paper

TitleSolution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1598, Page 10-23, Year 2002
Publish dateDec 11, 2000 (structure data deposition date)
AuthorsFeng, Y. / Likos, J.J. / Zhu, L. / Woodward, H. / Munie, G. / McDonald, J.J. / Stevens, A.M. / Howard, C.P. / De Crescenzo, G.A. / Welsch, D. ...Feng, Y. / Likos, J.J. / Zhu, L. / Woodward, H. / Munie, G. / McDonald, J.J. / Stevens, A.M. / Howard, C.P. / De Crescenzo, G.A. / Welsch, D. / Shieh, H.-S. / Stallings, W.C.
External linksBiochim. Biophys. Acta / PubMed:12147339
MethodsNMR (solution)
Structure data

PDB-1hov:
SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020
Method: SOLUTION NMR

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-I52:
N-{4-[(1-HYDROXYCARBAMOYL-2-METHYL-PROPYL)-(2-MORPHOLIN-4-YL-ETHYL)-SULFAMOYL]-4-PENTYL-BENZAMIDE

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / enzyme-inhibitor complex / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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