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Structure paper

TitleStructures of the complexes of a potent anti-HIV protein cyanovirin-n and high mannose oligosaccharides
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 34336-34342, Year 2002
Publish dateApr 3, 2009 (structure data deposition date)
AuthorsBotos, I. / O'Keefe, B.R. / Shenoy, S.R. / Cartner, L.K. / Ratner, D.M. / Seeberger, P.H. / Boyd, M.R. / Wlodawer, A.
External linksJ. Biol. Chem. / PubMed:12110688
MethodsX-ray diffraction
Resolution2.4 - 2.5 Å
Structure data

PDB-3gxy:
Crystal structure of cyanovirin-n complexed to a synthetic hexamannoside
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3gxz:
Crystal structure of cyanovirin-n complexed to oligomannose-9 (man-9)
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NHE:
2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID / pH buffer*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • nostoc ellipsosporum (bacteria)
KeywordsANTIVIRAL PROTEIN / CYANOVIRIN-N / HIV-INACTIVATING / DOMAIN-SWAPPING / GP120 / MAN-9 / OLIGOSACCHARIDE / Disulfide bond / Protein synthesis inhibitor

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