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Structure paper

TitleA covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase.
Journal, issue, pagesBiochemistry, Vol. 41, Page 8807-8818, Year 2002
Publish dateMay 13, 2002 (structure data deposition date)
AuthorsBossi, R.T. / Aliverti, A. / Raimondi, D. / Fischer, F. / Zanetti, G. / Ferrari, D. / Tahallah, N. / Maier, C.S. / Heck, A.J.R. / Rizzi, M. / Mattevi, A.
External linksBiochemistry / PubMed:12102623
MethodsX-ray diffraction
Resolution1.05 - 1.25 Å
Structure data

PDB-1lqt:
A covalent modification of NADP+ revealed by the atomic resolution structure of FprA, a Mycobacterium tuberculosis oxidoreductase
Method: X-RAY DIFFRACTION / Resolution: 1.05 Å

PDB-1lqu:
Mycobacterium tuberculosis FprA in complex with NADPH
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-ODP:
4-OXO-NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / NADP+ derivative / tuberculosis / Structural Genomics / PSI / Protein Structure Initiative / TB Structural Genomics Consortium / TBSGC / NADPH / FAD

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