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TitleDNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose.
Journal, issue, pagesBiochemistry, Vol. 41, Page 7217-7223, Year 2002
Publish dateFeb 7, 2002 (structure data deposition date)
AuthorsLafitte, D. / Lamour, V. / Tsvetkov, P.O. / Makarov, A.A. / Klich, M. / Deprez, P. / Moras, D. / Briand, C. / Gilli, R.
External linksBiochemistry / PubMed:12044152
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-1kzn:
Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CBN:
CLOROBIOCIN / antibiotic*YM

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsISOMERASE / topoisomerase / gyrase B / clorobiocin

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