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Structure paper

TitleCrystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Journal, issue, pagesChem. Biol., Vol. 9, Page 639-, Year 2002
Publish dateJan 9, 2002 (structure data deposition date)
AuthorsLenhart, A. / Weihofen, W.A. / Pleschke, A.E.W. / Schulz, G.E.
External linksChem. Biol. / PubMed:12031670
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1gsz:
Crystal Structure of a Squalene Cyclase in Complex with the Potential Anticholesteremic Drug Ro48-8071
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-C8E:
(HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE / C8E, detergent*YM

ChemComp-R71:
[4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE

ChemComp-HOH:
WATER

Source
  • alicyclobacillus acidocaldarius (bacteria)
KeywordsISOMERASE / CHOLESTEROL BIOSYNTHESIS / INHIBITOR OXIDOSQUALENE CYCLASE / MONOTOPIC MEMBRANE PROTEIN

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