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TitleLeukotriene A4 Hydrolase: Selective Abrogation of Leukotriene B4 Formation by Mutation of Aspartic Acid 375
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 99, Page 4215-, Year 2002
Publish dateMar 7, 2002 (structure data deposition date)
AuthorsRudberg, P.C. / Tholander, F. / Thunnissen, M.M.G.M. / Samuelsson, B. / Haeggstrom, J.Z.
External linksProc. Natl. Acad. Sci. USA / PubMed:11917124
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1gw6:
STRUCTURE OF LEUKOTRIENE A4 HYDROLASE D375N MUTANT
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-BES:
2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID

ChemComp-ACT:
ACETATE ION

ChemComp-IMD:
IMIDAZOLE

ChemComp-YB:
YTTERBIUM (III) ION

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / MUTAGENESIS STUDIES / ALPHA-BETA PROTEIN

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