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TitleThe structure of human recombinant aldose reductase complexed with the potent inhibitor zenarestat.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 58, Page 622-626, Year 2002
Publish dateApr 9, 2001 (structure data deposition date)
AuthorsKinoshita, T. / Miyake, H. / Fujii, T. / Takakura, S. / Goto, T.
External linksActa Crystallogr. ,Sect. D / PubMed:11914486
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1iei:
CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH THE INHIBITOR ZENARESTAT.
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-ZES:
[3-(4-BROMO-2-FLUORO-BENZYL)-7-CHLORO-2,4-DIOXO-3,4-DIHYDRO-2H-QUINAZOLIN-1-YL]-ACETIC ACID / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / Protein-inhibitor complex / NADP

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