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Structure paper

TitleSpecies-Specific Inhibition of Porphobilinogen Synthase by 4-Oxosebacic Acid
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 19792-19799, Year 2002
Publish dateMar 13, 2002 (structure data deposition date)
AuthorsJaffe, E.K. / Kervinen, J. / Martins, J. / Stauffer, F. / Neier, R. / Wlodawer, A. / Zdanov, A.
External linksJ. Biol. Chem. / PubMed:11909869
MethodsX-ray diffraction
Resolution1.7 - 1.9 Å
Structure data

PDB-1l6s:
Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4,7-Dioxosebacic Acid
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1l6y:
Crystal Structure of Porphobilinogen Synthase Complexed with the Inhibitor 4-Oxosebacic Acid
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-DSB:
4,7-DIOXOSEBACIC ACID

ChemComp-HOH:
WATER

ChemComp-4OX:
4-OXODECANEDIOIC ACID

ChemComp-GOL:
GLYCEROL

Source
  • escherichia coli (E. coli)
KeywordsLYASE / DEHYDRATASE

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